Positive and Negative Selection in Murine Ultraconserved Noncoding Elements
نویسندگان
چکیده
منابع مشابه
Positive and negative selection in murine ultraconserved noncoding elements.
There are many more selectively constrained noncoding than coding nucleotides in the mammalian genome, but most mammalian noncoding DNA is subject to weak selection, on average. One of the most striking discoveries to have emerged from comparisons among mammalian genomes is the hundreds of noncoding elements of more than 200 bp in length that show absolute conservation among mammalian orders. T...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2011
ISSN: 1537-1719,0737-4038
DOI: 10.1093/molbev/msr093